2. Metabolic Disease

Metabolic Disease

Metabolic Disease

Related Products

PDF 53.7 MB

Metabolic diseases is defined by a constellation of interconnected physiological, biochemical, clinical, and metabolic factors that directly increases the risk of cardiovascular disease, type 2 diabetes mellitus, and all cause mortality. Associated conditions include hyperuricemia, fatty liver (especially in concurrent obesity) progressing to nonalcoholic fatty liver disease, polycystic ovarian syndrome (in women), erectile dysfunction (in men), and acanthosis nigricans. Metabolic disease modeling is an essential component of biomedical research and a mandatory prerequisite for the treatment of human disease. Somatic genome editing using CRISPR/Cas9 might be used to establish novel metabolic disease models.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-E70978
    6-Phosphogluconolactonase, Leuconostoc mesenteroides
    6-Phosphogluconolactonase, Leuconostoc mesenteroides is an enzyme in the pentose phosphate pathway. 6-Phosphogluconolactonase, Leuconostoc mesenteroides converts 6-phosphogluconolactone to 6-phosphogluconate.
    6-Phosphogluconolactonase, Leuconostoc mesenteroides
  • HY-E70979
    Acetyl esterase, Microbial 98%
    Acetyl esterase, Microbial (EC 3.1.1.72) catalyzes the hydrolysis of acetyl esters.
    Acetyl esterase, Microbial
  • HY-E70980
    Achromopeptidase, Bacteria
    Achromopeptidase, Bacteria (EC 3.4.21.50) catalyses the following chemical reaction:Preferential cleavage:Lys-, including-Lys-Pro-. Achromopeptidase, Bacteria (EC 3.4.21.50) is isolated from Achromobacter lyticus.
    Achromopeptidase, Bacteria
  • HY-E70981
    Alanine Racemase, Bacillus stearothermophilus
    Alanine Racemase, Bacillus stearothermophilus (EC 5.1.1.1) is involved in alanine, aspartate and D-alanine metabolism. Alanine Racemase, Bacillus stearothermophilus (EC 5.1.1.1) monomer is composed of two domains, an eight-stranded α/β barrel at the N-terminus and a C-terminal domain.
    Alanine Racemase, Bacillus stearothermophilus
  • HY-E70982
    Amine Oxidase, Bovine Plasma
    Amine Oxidase, Bovine Plasma (EC 1.4.3.21) is an enzyme involved in the metabolism, oxidation, and inactivation of histamine within the digestive tract.
    Amine Oxidase, Bovine Plasma
  • HY-E70983
    Antistreptolysin O, Human
    Antistreptolysin O, Human is a hemolysin produced by group A streptococci. As a protein antigen, Antistreptolysin O, Human triggers an antibody response in the body.
    Antistreptolysin O, Human
  • HY-E70984
    Apotryptophanase, Escherichia coli
    Apotryptophanase, Escherichia coli (EC 4.1.99.1) hydrolizes tryptophan and is capable of catalyzing α,β-elimination reactions with a number of substituted amino acids, including S-methyl-, S-ethyl-and S-benzyl-L-cysteine. DTNB inactivates tryptophanase.
    Apotryptophanase, Escherichia coli
  • HY-E70985
    Auto-Activated Protein Kinase, Bovine
    Auto-Activated Protein Kinase, Bovine phosphorylates and inactivates protein phosphatase 2A. Auto-Activated Protein Kinase, Bovine is also involved in cytoskeleton organization and other signal transduction processes.
    Auto-Activated Protein Kinase, Bovine
  • HY-E70986
    Carbonic Anhydrase I, Human
    Carbonic Anhydrase I, Human (EC 4.2.1.1) is a zinc metalloenzyme that catalyzes the hydration of carbon dioxide to form carbonic acid. Carbonic Anhydrase I participates in a variety of important physiological processes, such as the maintenance of pH and carbon dioxide homeostasis, the transport of bicarbonate and carbon dioxide, biosynthetic reactions, bone resorption, calcification, and tumorigenesis.
    Carbonic Anhydrase I, Human
  • HY-E70987
    Chloroperoxidase, Caldariomyces fumago
    Chloroperoxidase, Caldariomyces fumago (EC 1.11.1.10) is an extracellular heme glycoenzyme containing ferriprotoporphyrin IX as the prosthetic group. Chloroperoxidase, Caldariomyces fumago (EC 1.11.1.10) is a peroxide-dependent chlorinating enzyme. It also catalyzes peroxidase-, catalase-and cytochrome P450-type reactions of dehydrogenation, H2O2 decomposition and oxygen insertion, respectively.
    Chloroperoxidase, Caldariomyces fumago
  • HY-E70988
    Defibrase, Bothrops atrox snake
    Defibrase, Bothrops atrox snake is a fibrinogen-reducing agent with hemostatic properties and can be used in thrombosis research.
    Defibrase, Bothrops atrox snake
  • HY-E70989
    D-Fructose Dehydrogenase, Gluconobacter industrius
    D-Fructose Dehydrogenase, Gluconobacter industrius (EC 1.1.99.11) is a heterotrimeric membrane-bound enzyme commonly seen in various Gluconobacter sp. especially in Gluconobacter japonicus (Gluconobacter industrius) .D-Fructose Dehydrogenase consists of subunits I (67kDa), II (51 kDa), and III (20 kDa) and catalyzes the oxidation of D-fructose to produce 5-keto-D-fructose. D-Fructose Dehydrogenase is a flavoprotein-cytochrome c complex with subunits I and II covalently bound to flavin adenine dinucleotide (FAD) and heme C as prosthetic groups, respectively.
    D-Fructose Dehydrogenase, Gluconobacter industrius
  • HY-E70990
    Diaphorase (NADH), Bacillus megaterium
    Diaphorase (NADH), Bacillus megaterium (EC 1.6.99.3) is an enzyme that catalyzes the chemical reaction NAD (P)H + H+ + a quinone? NAD (P)+ + a hydroquinone. The 4 substrates of this enzyme are NADH, NADPH, H+, and quinone, whereas its 3 products are NAD+, NADP+, and hydroquinone.
    Diaphorase (NADH), Bacillus megaterium
  • HY-E70991
    D-Ribulose-5-phosphate 3-Epimerase, Baker's yeast (S. cerevisiae)
    D-Ribulose-5-phosphate 3-Epimerase, Baker's yeast (S. cerevisiae) (EC 5.1.3.1) is a metalloenzyme that primarily utilizes divalent zinc ions (Zn2+) for catalysis.
    D-Ribulose-5-phosphate 3-Epimerase, Baker's yeast (S. cerevisiae)
  • HY-E70992
    Eosinophil Peroxidase, Human
    Eosinophil Peroxidase, Human (EC 1.11.1.7) is an enzyme found in eosinophils (innate immune cells of humans and mammals). Eosinophil Peroxidase, Human (EC 1.11.1.7) is a heme peroxidase whose activities include oxidizing halide ions to reactive oxygen species with bactericidal effects, disrupting bacterial cell walls with cations, and performing post-translational modifications on protein amino acid residues.
    Eosinophil Peroxidase, Human
  • HY-E70993
    Erythrocytes Acetylcholinesterase, Human
    Erythrocytes Acetylcholinesterase, Human (EC 3.1.1.7) for research on enzyme activity and red blood cell function.
    Erythrocytes Acetylcholinesterase, Human
  • HY-E70994
    Fructose-6-phosphate Kinase, Bacillus stearothermophilus
    Fructose-6-phosphate Kinase, Bacillus stearothermophilus (EC 2.7.1.11) is an important enzyme in glucose metabolism. Fructose-6-phosphate Kinase, Bacillus stearothermophilus (EC 2.7.1.11) catalyzes the hydrolysis of fructose-1,6-bisphosphate to fructose-6-phosphate and inorganic phosphate.
    Fructose-6-phosphate Kinase, Bacillus stearothermophilus
  • HY-E70995
    Galactose-1-phosphate Uridyltransferase, Galactose-adapted yeast
    Galactose-1-phosphate Uridyltransferase, Galactose-adapted yeast (EC 2.7.7.12) facilitates the simultaneous conversion of uridine diphosphoglucose (UDP-glucose) and galactose-1-phosphate (gal-1P) to uridine diphosphogalactose (UDP-galactose) and glucose-1-phosphate.
    Galactose-1-phosphate Uridyltransferase, Galactose-adapted yeast
  • HY-E70996
    Gamma-Glutamyl Transferase, Human
    Gamma-Glutamyl Transferase, Human (EC 2.3.2.2) is an enzyme capable of transferring the γ-glutamyl functional group. Gamma-Glutamyl Transferase, Human (EC 2.3.2.2) catalyzes the transfer of the γ-glutamyl group of glutathione to a receptor, which can be an amino acid, peptide, or water (to produce glutamate).
    Gamma-Glutamyl Transferase, Human
  • HY-E70997
    Glycopeptidase A, Almonds 98%
    Glycopeptidase A, Almonds (EC 3.5.1.52) is an enzyme that catalyzes a chemical reaction that cleaves a N4-(acetyl-beta-D-glucosaminyl)asparagine residue in which the glucosamine residue may be further glycosylated, to yield a (substituted) N-acetyl-beta-D-glucosaminylamine and a peptide containing an aspartate residue. Glycopeptidase A, Almonds (EC 3.5.1.52) belongs to the family of hydrolases, specifically those acting on carbon-nitrogen bonds other than peptide bonds in linear amides.
    Glycopeptidase A, Almonds
Cat. No. Product Name / Synonyms Application Reactivity